If you are looking for an autoimmunity panel blood test in Chandigarh, Altus Lab offers a comprehensive immunology diagnostic panel with free home collection across Chandigarh, Mohali, and Panchkula. Autoimmune diseases occur when the immune system mistakenly attacks the body’s own tissues. Because symptoms are often vague — fatigue, joint pain, rashes, and recurrent fevers — autoimmune conditions are frequently misdiagnosed or diagnosed late. An early and accurate blood test is therefore essential for timely treatment.
Our lab is founded and led by an Ex-PGIMER Chandigarh doctor with over 13 years of specialist diagnostic experience. Because we operate our own in-house laboratory, we process every sample on-site — which means faster, more reliable results than outsourced collection centres. Most autoimmunity panel reports are therefore ready within 4 hours of sample collection. Doctors at PGIMER, GMCH-32, GMCH-16, Fortis Mohali, Max Hospital, and all major Tricity rheumatology clinics accept our reports.
What Is an Autoimmunity Panel Test?
An autoimmunity panel is a group of blood tests that detect the presence of autoantibodies — antibodies the immune system produces against the body’s own proteins, tissues, or organs. These tests help rheumatologists and immunologists at PGIMER Chandigarh diagnose conditions such as Systemic Lupus Erythematosus (SLE), Rheumatoid Arthritis, Sjögren’s Syndrome, Antiphospholipid Syndrome, Myositis, and Scleroderma. Consequently, the autoimmunity panel is one of the most clinically important diagnostic tools in modern internal medicine.
Autoimmunity Panel — Tests Included at Altus Lab Chandigarh
| # | Test | Associated Condition(s) | Clinical Significance |
|---|---|---|---|
| 1 | ANA (Antinuclear Antibody) | SLE, Sjögren’s, Scleroderma, Mixed Connective Tissue Disease | Primary screening test for systemic autoimmune disease; positive in over 95% of SLE cases |
| 2 | Anti-dsDNA (Anti-double stranded DNA) | Systemic Lupus Erythematosus (SLE) | Highly specific for SLE; levels correlate with disease activity and lupus nephritis |
| 3 | Anti-Sm (Anti-Smith Antibody) | SLE | Highly specific for SLE though less sensitive than anti-dsDNA |
| 4 | RF (Rheumatoid Factor) | Rheumatoid Arthritis, Sjögren’s Syndrome | Elevated in 70–80% of RA patients; also positive in other autoimmune and infectious conditions |
| 5 | Anti-CCP (Anti-Cyclic Citrullinated Peptide) | Rheumatoid Arthritis | More specific than RF for RA; can be positive years before clinical symptoms appear |
| 6 | Anti-SSA / Anti-Ro | Sjögren’s Syndrome, SLE, Neonatal Lupus | Important in pregnant women — associated with neonatal heart block in babies |
| 7 | Anti-SSB / Anti-La | Sjögren’s Syndrome | More specific for primary Sjögren’s when positive alongside Anti-SSA |
| 8 | Anticardiolipin Antibodies (IgG, IgM) | Antiphospholipid Syndrome (APS) | Associated with blood clots, recurrent miscarriage, and stroke in young patients |
| 9 | Anti-Scl-70 (Anti-Topoisomerase I) | Systemic Sclerosis (Scleroderma) | Marker for diffuse cutaneous scleroderma with high risk of lung involvement |
| 10 | CRP (C-Reactive Protein) | Active inflammation — all autoimmune conditions | Indicates current inflammatory activity; elevated during flares |
| 11 | ESR (Erythrocyte Sedimentation Rate) | Non-specific inflammation marker | Commonly elevated in active autoimmune disease; used alongside CRP for disease monitoring |
| 12 | Complement C3 and C4 | SLE, Antiphospholipid Syndrome | Low complement levels indicate active SLE, particularly lupus nephritis |
Who Should Get an Autoimmunity Blood Test in Chandigarh?
The following groups should consider getting an autoimmunity panel. Because autoimmune diseases often have a slow, insidious onset, early testing is especially important:
- Adults with unexplained joint pain, morning stiffness, or swelling lasting more than 6 weeks
- Patients with persistent fatigue, unexplained fever, or recurrent mouth ulcers
- Women with a history of recurrent miscarriage — for Antiphospholipid Syndrome screening
- Patients with a butterfly-shaped rash on the face (malar rash), which is consequently characteristic of SLE
- Individuals with dry eyes and dry mouth — for Sjögren’s Syndrome evaluation
- Patients with skin tightening or Raynaud’s phenomenon — for Scleroderma screening
- Anyone with a family history of autoimmune disease, as genetic predisposition is significant
- Patients referred by rheumatologists, internists, or gynaecologists at PGIMER or GMCH-32
ANA Test — Understanding Your Result
The ANA (Antinuclear Antibody) test is the primary screening test for systemic autoimmune diseases. A positive ANA result at a titre of 1:80 or higher is considered clinically significant. However, a positive ANA alone does not diagnose any specific disease — it simply indicates that further testing is needed. Importantly, a low-titre positive ANA (1:40) can be found in up to 20% of healthy adults and is therefore not necessarily abnormal.
When ANA is positive, the pattern reported — homogeneous, speckled, nucleolar, or centromere — provides additional diagnostic guidance. For example, a homogeneous pattern with elevated anti-dsDNA strongly suggests SLE. A centromere pattern, on the other hand, is associated with limited systemic sclerosis (CREST syndrome). Your rheumatologist at PGIMER Chandigarh will consequently interpret the ANA pattern alongside the other autoantibody results.
Normal Ranges — Autoimmunity Panel
| Test | Normal / Negative Range | Note |
|---|---|---|
| ANA | Negative (<1:40 titre) | Titres of 1:80 and above are considered clinically significant |
| Anti-dsDNA | <10 IU/mL | Levels correlate with SLE disease activity |
| RF | <14 IU/mL | Mildly elevated RF also occurs in healthy elderly patients |
| Anti-CCP | <20 U/mL | Highly specific for Rheumatoid Arthritis |
| Anticardiolipin IgG | <15 GPL units | Must be positive on two occasions 12 weeks apart for APS diagnosis |
| C3 | 90–180 mg/dL | Low C3 and C4 together suggest active lupus nephritis |
| C4 | 16–47 mg/dL | Persistently low C4 with positive ANA warrants urgent rheumatology review |
| CRP | <5 mg/L | Elevated during active inflammatory flares |
Why Choose Altus Lab for Autoimmunity Testing in Chandigarh?
- Founded by an Ex-PGIMER Chandigarh Doctor — specialist immunology diagnostics with 13+ years of experience
- Own In-House Laboratory — all samples processed on-site; no outsourcing, no delays, no chain-of-custody errors
- Reports in 4 Hours — same-day results accepted directly at PGIMER rheumatology and immunology departments
- Free Home Collection — across Chandigarh, Mohali, Panchkula, Zirakpur, and Kharar, 7:30 AM to 9:30 PM daily
- Reports Accepted Everywhere — PGIMER, GMCH-32, GMCH-16, Fortis Mohali, Max Hospital, and all Tricity rheumatology clinics
- Digital Reports via WhatsApp and Email — for instant sharing with your rheumatologist
Frequently Asked Questions — Autoimmunity Blood Test in Chandigarh
My ANA came back positive. Does that mean I have lupus?
Not necessarily. A positive ANA is a screening result — it indicates the need for further testing, not a definitive diagnosis of any disease. Up to 20% of healthy adults can have a low-titre positive ANA. Your rheumatologist will therefore order additional specific tests such as anti-dsDNA and complement levels before making any diagnosis of SLE.
What is the difference between RF and Anti-CCP for Rheumatoid Arthritis?
Rheumatoid Factor (RF) is elevated in 70–80% of RA patients but is not specific — it can also be elevated in other conditions including Sjögren’s Syndrome, hepatitis, and even healthy elderly adults. Anti-CCP, on the other hand, is highly specific for RA and can be positive years before symptoms appear. Consequently, testing both together gives your rheumatologist the most complete picture.
Can an autoimmunity panel be done at home in Chandigarh?
Yes. Altus Lab provides free home sample collection for the complete autoimmunity panel across Chandigarh, Mohali, and Panchkula. Call 0172-5017001 or send a WhatsApp message to book a convenient time slot.
I have been having recurrent miscarriages. Which test should I get?
Recurrent miscarriage is one of the key clinical presentations of Antiphospholipid Syndrome (APS). You should therefore get Anticardiolipin Antibody (IgG and IgM) and Anti-Beta-2 Glycoprotein testing, ideally alongside ANA. Altus Lab includes these in our autoimmunity panel. Please consult your gynaecologist at PGIMER or Fortis Mohali for interpretation.
How long do autoimmunity panel results take at Altus Lab?
Most autoimmunity panel results including ANA, RF, Anti-CCP, CRP, and ESR are ready within 4 hours. Specific antibodies such as anti-dsDNA, Anti-SSA, and Anticardiolipin may take up to 24–48 hours depending on the test methodology. We will inform you of the exact turnaround at the time of booking.
Book Your Autoimmunity Panel Test in Chandigarh Today
Autoimmune diseases are more common in India than most people realise — and early diagnosis is the single most important factor in preventing organ damage and achieving remission. If you or your doctor suspects an autoimmune condition, get a comprehensive panel at Altus Lab and take the results to your rheumatologist or internist at PGIMER, Fortis Mohali, or GMCH-32.
Call Now: 0172-5017001 / 0172-5017002
Available: 7:30 AM – 9:30 PM Daily
Free Home Collection: Chandigarh | Mohali | Panchkula | Zirakpur
Founded by Ex-PGIMER Doctor | Own In-House Lab | Reports in 4 Hours