Blocking folate receptor autoantibody
- What it detects
- Antibodies that attach to the folate receptor (FRα) and stop folate from binding to it.
- What a positive result suggests
- Folate may not be entering the brain through its main receptor pathway.
Detect Folate Receptor Autoantibodies (FRAbs) associated with Autism Spectrum Disorder (ASD) and Cerebral Folate Deficiency (CFD) through specialised FRAT testing by Altus Diagnostic Pvt. Ltd. Every test is conducted under the clinical supervision of Dr. Alok Gupta — MD Pathology, Ex-PGIMER, Chandigarh, bringing 12+ years of diagnostic expertise.
Talk directly to our team. Lines open 7:30 AM to 9:30 PM, every day.
Our lines are closed for the night. Book now and we'll call you after 7:30 AM to confirm.
Home collection across India
NABL-accredited reference lab
The key details of the test, before you book.

NABL-accredited laboratory
Certificate No. M-0828
Altus Medical Laboratory, SCO 35, Sector 16-D, Chandigarh
View certificate
FRAT test
₹8,500
All-India home collection included
Your sample is tested at our own reference lab in Chandigarh. It is not passed on to another lab, so there is no third-party margin and no extra handling.
An NABL-accredited reference lab based in Chandigarh. Samples from across India are tested at this facility.
Doctors and patients choose us for the quality of our work and the authenticity of our reports.
Every test is overseen by Dr. Alok Gupta, who has led Altus Lab since 2013.
What happens to your child's sample, from the home visit until it reaches our lab in Chandigarh.


No fasting needed. Our team will guide you.
Your child doesn't need to skip meals before the blood draw. Before the visit, we call to confirm the details and answer your questions, so you know exactly what will happen.
Call or WhatsApp us, or leave your details here and we call you back.
We confirm the ₹8,500 price and your collection slot. You pay only after the sample is collected.
Your full address with PIN code and location, a mobile number, your child's name, age and sex, and a time that suits you.
We assign a phlebotomist suited to your child's age, trained to collect blood from young children gently and calmly.
Your child's sample is held at the required low temperature to protect its quality, then air-lifted to our reference lab in Chandigarh through international-grade cold-chain logistics.
Counted from the day the sample reaches our reference lab. You receive it on WhatsApp and email.
MD Pathology, Ex-PGIMER, Chandigarh. Lab Director and founder of Altus Lab.
Every FRAT test at Altus is supervised by Dr. Gupta. If you have questions about the test, the sample or the report, you can speak with him directly before you book.
Neurologists and paediatricians across India refer families to us for the FRAT test.


Folate is a B vitamin the brain needs to develop and work normally. It reaches the brain through a carrier called the folate receptor alpha. In some children and adults, the immune system makes antibodies against this receptor.
The FRAT test checks whether these antibodies are present in the blood.
Doctors usually suggest the test when a child has autism spectrum disorder (ASD), developmental delay or regression, speech delay, seizures, or other neurodevelopmental concerns, and they want to look into cerebral folate deficiency (CFD).
Not sure whether FRAT is right for your child? Discuss it with your doctor, or call us and we'll explain what the test covers.
What it can show
A positive result shows these antibodies are present, which may affect how much folate reaches the brain. Your doctor reads it alongside your child's history and other tests.
What it can't show
FRAT is not a test for autism and does not diagnose any condition on its own. A negative result doesn't rule out other causes of your child's symptoms.
A routine folate test measures how much folate is in the blood. The FRAT test looks for two antibodies that can stop folate reaching the brain, which is why a child with normal blood folate can still be advised a FRAT test.
| Comparison | Standard folate test | FRAT test |
|---|---|---|
| What it checks | How much folate is in the blood | Blocking and binding antibodies against the folate receptor that carries folate into the brain |
| Finds folate receptor antibodies | No | Yes, both blocking and binding types |
| Usually used for | Routine checks of folate levels and nutrition | Specialist investigation when a doctor is looking into cerebral folate deficiency, for example in children with ASD, developmental delay or seizures |
A positive result on either component is not a diagnosis. Your doctor reads it together with your child's history and other tests, and decides the next steps.
We collect samples at home in these cities and across the rest of India.
Don't see your city? We serve all towns and cities across India. Call +91 628 421 4977 to confirm availability in your area.
The FRAT (Folate Receptor Autoantibody Test) is a blood test that checks for antibodies against the folate receptor alpha, the carrier that helps folate reach the brain. It looks for two types: blocking and binding antibodies.
No. The FRAT test does not diagnose autism or any other condition. It shows whether folate receptor antibodies are present. Doctors read the result together with the child's history and other tests, usually when they are looking into cerebral folate deficiency. It is most often advised for children with autism spectrum disorder (ASD) or signs such as:
These signs have many possible causes. Having one or more of them does not mean a child has folate receptor antibodies, and the test cannot confirm or rule out autism. Please speak to your child's doctor before booking.
The FRAT test checks for folate receptor antibodies, one of the known causes of cerebral folate deficiency (CFD), a condition in which too little folate reaches the brain. Because it is a simple blood test, doctors often advise it first when they suspect CFD in a child with autism or developmental concerns. Confirming CFD itself needs a spinal fluid test (CSF 5-MTHF), which only your doctor can advise.
The FRAT test is not a test for ADHD. Some doctors advise it for children with attention difficulties when these come with other signs, such as speech or developmental delay, loss of skills or seizures, to check whether folate receptor antibodies may be playing a part. Your child's doctor is the best person to decide whether it is needed.
Doctors may advise the FRAT test when a child has speech delay, developmental delay or loss of skills already learned, especially alongside autism, seizures or movement problems. A positive result can help your doctor decide whether folinic acid (leucovorin) treatment is worth considering. Many children with delays test negative, because delays have many causes.
Doctors may advise the FRAT test for children with seizures that are hard to control, unexplained movement problems such as dystonia, loss of skills, or other neurological symptoms where cerebral folate deficiency is a possibility. It is one part of a wider evaluation by a paediatric neurologist or your child's doctor.
At Altus Lab, the FRAT test costs ₹8,500. Home sample collection is included at no extra cost, and your sample is kept cold and air-lifted to our reference lab in Chandigarh. The FRAT test cost is the same in every city in India.
We test FRAT in-house at our own reference lab, so there is no third-party lab margin and no extra handling. Altus Lab is an NABL-accredited reference lab where samples from across India are tested, and we do not offer incentives for referrals. Every test is supervised by Dr. Alok Gupta, MD Pathology, Ex-PGIMER, Chandigarh.
Yes. We serve all towns and cities across India, including Bengaluru, Hyderabad, Chennai, Kochi, Delhi NCR, Mumbai and Pune. Call +91 628 421 4977 to confirm availability in your area, and we will send a phlebotomist suited to your child's age.
You pay only after the sample has been collected at your home. Our team confirms the price of ₹8,500 when you book.
No fasting is needed. Our team calls you before the visit to confirm the details and explain what to expect.
The report is ready in 5–7 working days from the day the sample reaches our reference lab. Your sample is kept at the required low temperature and air-lifted to Chandigarh through cold-chain logistics, usually reaching us within 1 to 3 days. We send the report on WhatsApp and email.
Altus Lab is NABL accredited, and our reports are accepted at PGI, AIIMS and major hospitals. Every FRAT report is supervised by Dr. Alok Gupta, MD Pathology, Ex-PGIMER, Chandigarh.
₹8,500. Talk directly to our team, 7:30 AM to 9:30 PM, every day.
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