Advanced OAT Test in India — Urine Metabolomics | 140+ Biomarkers | ₹18,000 | Altus Diagnostic
Test Price
₹18,000
Sample Type
First Morning Urine — Kit at Home
Fasting Required
10–12 Hours
Technology
LC-MS/MS
Report Delivery
7 Working Days
Accreditation
NABL Accredited Laboratory
What Is the Advanced OAT Test?
Your blood reports are normal. Your thyroid is fine. Your haemoglobin is adequate. Yet you feel exhausted, mentally foggy, and physically unwell — and nobody can explain why. Or your child has been diagnosed with autism, ADHD, or a developmental delay, and you sense that something deeper is happening beneath the surface of that diagnosis. This is precisely the clinical gap that the Advanced OAT Test was designed to fill.
The Advanced Organic Acids Test (OAT) at Altus Diagnostic is a comprehensive urine metabolomics profile that generates a complete picture of how your body’s most critical biochemical systems are actually functioning at the cellular level. Using Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) — the gold standard in clinical metabolomics — the test simultaneously measures over 140 urinary organic acid biomarkers and calculates 21 functional ratio indices across nine distinct metabolic domains.
Organic acids are small-molecule metabolic byproducts excreted in urine. They are the chemical footprints left behind by enzymatic reactions taking place throughout your body — in your gut microbiome, your mitochondria, your liver detoxification pathways, your brain neurotransmitter synthesis, your vitamin metabolism, and your amino acid processing systems. When these footprints deviate from expected patterns, they reveal precisely where — and how seriously — the underlying biochemical machinery has broken down.
The critical distinction: Conventional blood tests tell you what is present in your bloodstream at a single moment. The Advanced OAT Test tells you whether those molecules are being correctly processed and utilised by the enzyme systems that depend on them. The difference is between knowing your car has fuel and knowing whether your engine is actually burning it efficiently.
What the Advanced OAT Test Measures — 9 Clinical Domains
The Advanced OAT Test evaluates nine interconnected metabolic systems in a single urine sample. Its clinical power comes from seeing all nine simultaneously — revealing the relationships between gut dysbiosis and mitochondrial impairment, between neurotransmitter imbalances and B vitamin deficiencies, between glutathione depletion and oxidative DNA damage.
🦠 1. Gut Microbiome & Dysbiosis
Identifies yeast, fungal, bacterial, and Clostridia metabolites — revealing microbial overgrowths that drive systemic inflammation, impair detoxification, block neurotransmitter production, and deplete essential nutrients, often without obvious gastrointestinal symptoms. Clostridia toxins such as HPHPA and p-cresyl sulfate have been strongly linked to autism and ADHD behaviours.
⚡ 2. Mitochondrial Function & Energy
Evaluates all seven Krebs cycle intermediates plus six calculated efficiency ratios — identifying exactly where cellular energy production is blocked. Impaired mitochondrial function is the metabolic foundation of chronic fatigue, brain fog, poor exercise tolerance, and developmental delays in children.
🧠 3. Neurotransmitter Metabolism
Measures urinary metabolites of dopamine, serotonin, and the kynurenine pathway — providing a validated non-invasive window into central neurochemistry. Imbalances explain depression, anxiety, ADHD, autism, OCD, and neurodegenerative conditions including Parkinson’s disease.
💊 4. Nutritional & Vitamin Status
Identifies functional deficiencies of B12, folate, B6, B5, CoQ10, and Vitamin C — even when standard serum levels appear normal. Elevated methylmalonic acid (MMA) confirms functional B12 deficiency despite normal serum B12. This precision is impossible with blood tests alone.
🧬 5. Amino Acid Metabolism
Profiles 17 amino acids plus 20 branched-chain ketoacid catabolism markers — identifying protein digestion deficits, enzyme deficiencies affecting leucine, valine, phenylalanine and methionine processing, and 10 acylglycine fatty acid oxidation markers that reveal inherited or acquired metabolic enzyme defects.
🛡️ 6. Detoxification & Oxidative Stress
Directly measures glutathione status (GSH/GSSG ratio), DNA oxidative damage (8-OHdG), lipid peroxidation (MDA), and direct environmental toxin exposure — including BPA, BPB, xylene, and acrolein. These 18 markers reveal the toxic burden the body is carrying silently, completely invisible to conventional testing.
🔥 7. Fatty Acid & Ketone Metabolism
Evaluates beta-oxidation enzyme efficiency through nine markers — identifying metabolic blocks in fat-to-energy conversion that cause unexplained fatigue, hypoglycaemia, poor fasting tolerance, and impaired recovery from exercise.
🔄 8. Methylation & One-Carbon Metabolism
Evaluates the MMA/FIGLU ratio, the methionine/2-hydroxybutyric ratio, and pyrimidine metabolites — quantifying methylation cycle sufficiency and identifying which specific B vitamins are limiting DNA repair, gene expression, detoxification, and neurotransmitter regulation.
📊 9. Functional Ratio Indices (21)
Calculates 21 inter-pathway ratios across mitochondrial function, neurotransmitter balance, methylation, and redox status — providing clinical insights into biochemical system dynamics that individual metabolite values alone cannot deliver.
Complete Advanced OAT Test Marker List — 140+ Biomarkers
| Category | Markers [Count] | Biomarkers Measured |
|---|---|---|
| GUT MICROBIOME MARKERS | ||
| Yeast & Fungal | [9] | Citramalic acid · 5-Hydroxymethyl-2-Furoic acid (Aspergillus) · 3-Oxoglutaric acid · Furan-2,5-dicarboxylic acid (Aspergillus) · Furancarbonylglycine (Aspergillus) · Tartaric acid (Aspergillus) · Arabinose · Carboxycitric acid · Tricarballylic acid (Fusarium) |
| Bacterial Dysbiosis | [9] | Hippuric acid · Phenylacetic acid · 2-Hydroxyphenylacetic acid · 4-Hydroxybenzoic acid · Benzoic acid · Benzoylformic acid · DHPPA · Trimethylamine-N-Oxide (TMAO) · 4-Hydroxybenzoic acid isomer |
| Clostridia Species | [5] | 4-Hydroxyphenylacetic acid (C. difficile) · HPHPA (C. sporogenes, C. botulinum) · p-Cresyl sulfate (C. difficile) · 3-Indoleacetic acid (Clostridia spp.) · 3-Hydroxypropionic acid |
| Oxalate Metabolites | [3] | Glyceric acid · Glycolic acid · Oxalic acid |
| MITOCHONDRIAL & ENERGY MARKERS | ||
| Glycolytic Cycle | [2] | Lactic acid · Pyruvic acid |
| Krebs Cycle | [7] | Succinic acid · Fumaric acid · Malic acid · α-Ketoglutaric acid · Cis-aconitic acid · Citric acid · Isocitric acid |
| Mitochondrial Amino Acid & Redox | [7] | 3-Methylglutaric acid · 3-Methylglutaconic acid · 2-Hydroxyglutaric acid · 2-Methylglutaric acid · 3-Hydroxyglutaric acid · Succinylacetone · NAD+ (Nicotinamide adenine dinucleotide) |
| Ketone & Fatty Acid Oxidation | [9] | 3-Hydroxybutyric acid · Acetoacetic acid · Adipic acid · Suberic acid · Sebacic acid · Ethylmalonic + Methylsuccinic acid · Malonic acid · Tiglylglycine · 2-Pimelic acid |
| NEUROTRANSMITTER MARKERS | ||
| Catecholamines (Dopamine / Norepinephrine) | [5] | Vanilmandelic acid — VMA · Homovanillic acid — HVA · HVA/VMA Ratio · Dihydroxyphenylacetic acid — DOPAC · HVA/DOPAC Ratio |
| Serotonin & Kynurenine Pathway | [4] | 5-Hydroxyindole-3-acetic acid — 5-HIAA (serotonin) · 2,3-Pyridinedicarboxylic acid (Quinolinic acid) · Kynurenic acid · Picolinic acid |
| Folate-Dependent Pyrimidines | [2] | Uracil · Thymine |
| NUTRITIONAL MARKERS | ||
| Functional Vitamin Status | [10] | Methylmalonic acid — MMA (B12) · FIGLU (Folate) · Pyridoxic acid (B6) · Pantothenic acid (B5) · Glutaric acid · Ascorbic acid (Vitamin C) · 3-HMG (CoQ10 marker) · Mevalonic acid (Cholesterol biosynthesis) · N-Acetylcysteine (Glutathione precursor) · 2-Methylcitric acid (B12/propionyl-CoA) |
| DETOXIFICATION & OXIDATIVE STRESS MARKERS | ||
| Detox Capacity & Toxic Burden | [18] | Pyroglutamic acid (GSH/Redox) · Glutathione Reduced — GSH · Glutathione Disulfide — GSSG · GSH/GSSG Ratio · 2-Hydroxybutyric acid · Orotic acid (ammonia excess) · 2-Hydroxyhippuric acid (salicylates/GI) · 2-Methylhippuric acid (Xylene) · 3-/4-Methylhippuric acid (Xylene) · 8-OHdG (DNA oxidative damage) · 8-Hydroxyguanine · Bisphenol A — BPA · Bisphenol B — BPB · Acrolein · 3-Nitrotyrosine (nitrosative stress) · Malondialdehyde (lipid peroxidation) · 1,4-Dihydroxynonane mercapturic acid · 8-iso-Prostaglandin F2α |
| AMINO ACID MARKERS | ||
| Essential Amino Acids | [8] | Histidine · Isoleucine · Leucine · Lysine · Methionine · Phenylalanine · Threonine · Valine |
| Non-Essential Amino Acids | [9] | Alanine · Arginine · Aspartic acid · Cystine · Glutamic acid · Glycine · Proline · Tyrosine · Serine |
| Branched-Chain Ketoacids & Catabolism | [20] | 2-Hydroxyisovaleric acid · α-Ketoisovaleric acid · 3-Methyl-2-oxovaleric acid · 2-Hydroxyisocaproic acid · α-Ketoisocaproic acid · 2-Oxo-4-methiolbutyric acid · Mandelic acid · 3-Phenyllactic acid · Phenylpyruvic acid · Homogentisic acid · 4-Hydroxyphenyllactic acid · 4-Hydroxyphenylpyruvic acid · Xanthurenic acid · 3-Hydroxyisovaleric acid · N-Acetyl-L-aspartic acid · α-Ketobutyric acid · 4-Hydroxybutyric acid · O-Phosphorylethanolamine · Creatine · Argininosuccinic acid |
| Acylglycines (Fatty Acid Oxidation) | [10] | Butyrylglycine · Isobutyrylglycine · 3-Methylcrotonylglycine · 2-Methylbutyrylglycine · Isovalerylglycine · Valerylglycine · Hexanoylglycine · 3-Phenylpropionylglycine · Suberylglycine · Other acylglycine species |
| OTHER METABOLITES | ||
| Miscellaneous | [3] | Glucaric acid (Phase 1 detoxification) · Phosphoric acid (inorganic phosphate/minerals) · Creatinine (urinary dilution correction factor) |
21 Functional Ratio Indices — What Makes Advanced OAT Unique
Beyond raw metabolite values, the Advanced OAT Test calculates 21 clinically derived ratio indices that reveal the dynamic balance and efficiency of interconnected biochemical systems — providing insights that individual measurements cannot deliver on their own.
| Index Category | Ratio Indices | Clinical Significance |
|---|---|---|
| Mitochondrial Function [6] | Lactate/Pyruvate · Citrate/cis-Aconitate · cis-Aconitate/Isocitrate · α-KG/Succinate · Succinate/Fumarate · Fumarate/Malate | Identifies precisely which Krebs cycle step is inefficient; distinguishes aerobic vs anaerobic cellular metabolism |
| Neurotransmitter Balance [7] | HVA/VMA · HVA/DOPAC · Kynurenic/Xanthurenic · Kynurenic/Picolinic · Quinolinate/Kynurenate · Pyridoxic/Serotonin · Pyridoxic/Kynurenic | Reveals dopamine turnover dynamics, neuroprotective vs neurotoxic tryptophan metabolism, and B6 adequacy for neurotransmitter synthesis |
| Methylation & B-Vitamins [3] | Pyridoxic/Xanthurenic · MMA/FIGlu · Methionine/2-Hydroxybutyric | Quantifies methylation cycle sufficiency; identifies rate-limiting B vitamins in the methionine and folate cycles |
| Redox & Detoxification [4] | Ascorbate/Pyroglutamate · Glycine/Pyroglutamate · Serine/Pyroglutamate · Pantothenic/Pyroglutamate | Assesses glutathione regeneration capacity and antioxidant reserve; quantifies detoxification resilience against ongoing oxidative challenge |
| Nitrogen Balance [1] | Orotate/Arginine | Evaluates urea cycle efficiency and ammonia metabolism; identifies nitrogen metabolic imbalances linked to cognitive impairment and fatigue |
Who Should Consider the Advanced OAT Test?
The Advanced OAT Test is valuable for any individual — adult or child — whose clinical presentation involves unexplained symptoms, conditions that have responded poorly to standard treatment, or health goals requiring deeper metabolic insight than conventional testing provides.
🧒 Children — Neurodevelopmental Conditions
- Autism Spectrum Disorder (ASD)
- ADHD and attention disorders
- Speech delay and language regression
- Sensory processing disorder
- Developmental delays — unexplained
- Behavioural changes without clear cause
🧠 Brain and Mental Health
- Depression — especially treatment-resistant
- Anxiety and panic disorders
- Obsessive-compulsive disorder
- Parkinson’s disease and dementia (early markers)
- Brain fog and chronic poor concentration
- Seizure disorders
⚡ Energy and Fatigue Conditions
- Chronic Fatigue Syndrome / ME-CFS
- Fibromyalgia
- Post-COVID fatigue syndrome
- Poor recovery from exercise or illness
- Diabetes and insulin resistance
- Obesity and weight resistance
🦠 Gut and Digestive Disorders
- Irritable Bowel Syndrome (IBS)
- SIBO — Small Intestinal Bacterial Overgrowth
- Recurrent Candida and yeast infections
- Bloating and unexplained digestive symptoms
- Food sensitivities and intolerances
- Inflammatory Bowel Disease
☠️ Toxic Exposure and Detox Concerns
- Environmental chemical exposure — plastics, solvents
- Mycotoxin and mould-related illness
- Heavy metal toxicity
- Lyme disease and co-infections
- Occupational chemical exposure
- Impaired detoxification capacity
💊 Nutritional and Immune Conditions
- Unexplained nutrient deficiencies despite supplementation
- Autoimmune disorders
- Chronic inflammation
- Hormonal imbalances and thyroid dysfunction
- Cardiovascular disease and metabolic syndrome
- Preventive and optimisation health goals
Advanced OAT Test vs Conventional Blood Tests — What Is Different?
The Advanced OAT Test does not replace conventional blood testing — it fills the vast diagnostic gap between normal blood results and unexplained symptoms. Here is precisely what that difference looks like in clinical practice:
| Feature | Routine Blood Tests | Advanced OAT Test |
|---|---|---|
| Sample type | Blood — venepuncture required | ✓ Urine — completely non-invasive |
| Biomarkers measured | 10–30 isolated markers | ✓ 140+ metabolic biomarkers |
| Technology | Standard biochemistry | ✓ LC-MS/MS (gold standard) |
| What it shows | Static nutrient and hormone levels | ✓ Functional pathway activity |
| Gut microbiome | Not included | ✓ 23 gut microbial markers |
| Mitochondrial function | Not measured | ✓ 7 Krebs cycle + 6 ratio indices |
| Neurotransmitter metabolism | Not included | ✓ Dopamine, serotonin, kynurenine |
| Environmental toxin exposure | Not included | ✓ BPA, BPB, xylene, acrolein, 8-OHdG |
| Functional vitamin status | Serum level only — not functional | ✓ Intracellular functional markers (MMA, FIGLU, pyridoxic) |
| Glutathione status | Not routinely measured | ✓ GSH, GSSG and GSH/GSSG ratio |
| Collection location | Laboratory visit required | ✓ Home — kit delivered to you |
| Intervention guidance | Generic supplementation | ✓ Targeted personalised protocol |
Advanced OAT Test for Autism — What It Reveals in Children
The Advanced OAT Test has become a cornerstone investigation in functional medicine protocols for autism spectrum disorder (ASD). Children with autism consistently show distinct metabolomic profiles — and the OAT Test identifies these with high clinical specificity, providing actionable evidence for targeted intervention:
Common findings in children with autism on OAT testing:
Elevated Clostridia metabolites (HPHPA, p-cresyl sulfate) — neurotoxic bacterial metabolites that block dopamine synthesis, contributing to repetitive behaviours, irritability, and poor social engagement
Elevated yeast markers (Arabinose, Tartaric acid) — Candida overgrowth depletes glutathione and impairs detoxification, worsening neurological symptoms and increasing sensitivity to foods
Impaired Krebs cycle activity — low mitochondrial intermediates indicate cellular energy deficits that drive fatigue, poor motor control, and cognitive difficulties
Elevated oxidative stress markers (8-OHdG, Malondialdehyde) — oxidative damage to DNA and cell membranes reflecting inadequate antioxidant defence and glutathione depletion
Neurotransmitter imbalances — elevated HVA/VMA ratio, suppressed serotonin metabolites, and kynurenine pathway dysregulation affecting mood, focus, and behaviour
Functional B vitamin deficiencies — elevated MMA, FIGLU, and low pyridoxic acid, undermining neurotransmitter synthesis, methylation, and cellular energy production
Elevated Clostridia metabolites (HPHPA, p-cresyl sulfate) — neurotoxic bacterial metabolites that block dopamine synthesis, contributing to repetitive behaviours, irritability, and poor social engagement
Elevated yeast markers (Arabinose, Tartaric acid) — Candida overgrowth depletes glutathione and impairs detoxification, worsening neurological symptoms and increasing sensitivity to foods
Impaired Krebs cycle activity — low mitochondrial intermediates indicate cellular energy deficits that drive fatigue, poor motor control, and cognitive difficulties
Elevated oxidative stress markers (8-OHdG, Malondialdehyde) — oxidative damage to DNA and cell membranes reflecting inadequate antioxidant defence and glutathione depletion
Neurotransmitter imbalances — elevated HVA/VMA ratio, suppressed serotonin metabolites, and kynurenine pathway dysregulation affecting mood, focus, and behaviour
Functional B vitamin deficiencies — elevated MMA, FIGLU, and low pyridoxic acid, undermining neurotransmitter synthesis, methylation, and cellular energy production
Combining OAT with FRAT Test: For children with autism, the Advanced OAT Test and the FRAT Test (Folic Receptor Antibody Test) form a complementary diagnostic pair. The FRAT Test identifies whether folate transport to the brain is blocked by autoantibodies. The Advanced OAT Test reveals what is happening downstream — the gut dysbiosis, mitochondrial dysfunction, oxidative stress, and neurotransmitter imbalances that result from or accompany Cerebral Folate Deficiency. Together, they provide the complete metabolic picture needed for a multi-system, targeted treatment protocol.
How the Advanced OAT Test Works — Step by Step
Book and Receive Your Kit
Call or WhatsApp Altus Diagnostic at +91 89680 10467 to place your order. After booking confirmation, the Advanced OAT Test collection kit is dispatched to your home address anywhere in India within 1 to 2 working days. The kit contains all collection materials, detailed printed instructions, and a prepaid courier return label.
Prepare for Collection — 10–12 Hour Fast
Fast for 10 to 12 hours before collecting your sample. Water is permitted throughout. Avoid apple juice, grape juice, cranberries, raisins, and pineapple 48 hours before collection — these contain organic acids that can inflate specific test results. If you are taking antibiotics, antifungal medications, or high-dose B vitamins, contact our team first — a 5 to 7 day washout may be advisable.
Collect First Morning Urine at Home
Upon waking — after the overnight fast — collect your first morning urine using the materials in the kit. First morning urine provides the most concentrated organic acid profile, reflecting overnight metabolic activity without the diluting effect of daytime fluid intake. The collection takes approximately 5 minutes. No laboratory visit required.
Return Sample to Our Laboratory
Seal the sample as instructed and use the prepaid courier return label. The sample is a dry-format specimen stable at room temperature during transport. Contact our team to arrange pickup from your address, or dispatch directly using the courier label. Pickup is typically arranged within 24 to 48 working hours of notification.
Receive Your NABL Accredited Report in 7 Working Days
Within 7 working days of the laboratory receiving your sample, your complete NABL accredited Advanced OAT Test report is delivered digitally via email and WhatsApp. The report covers all 140+ biomarkers with measured values, reference ranges, and clinical flagging — alongside the 21 functional ratio indices and interpretive notes. Formatted for direct clinical use and sharing with your specialist.
Advanced OAT Test Preparation — Complete Guide
⚠️ Avoid 48 Hours Before Collection
- Apple juice, grape juice, cranberry products, raisins, pineapple — contain tartaric and malic acids that inflate OAT results
- Alcohol in any form — interferes with multiple metabolic pathways
- Unusually large citrus portions
⚠️ Consider Pausing 5–7 Days Before (consult our team first)
- Antibiotics — suppress bacterial dysbiosis markers
- Antifungal medications — suppress yeast markers
- High-dose B6, B12, folate supplements — alter nutritional marker values
- Probiotics — can temporarily normalise microbial marker patterns
✓ On the Day of Collection — Do This
- Complete your 10 to 12 hour overnight fast before collecting
- Drink only water during the fasting period
- Collect first morning urine immediately upon waking
- Follow the kit leaflet instructions precisely and completely
- Do not exercise before collecting — exercise elevates lactate and pyruvate
- Note all medications and supplements taken in the past 7 days on the kit paperwork
- Store the sample as directed in the kit until it is couriered
Conditions the Advanced OAT Test May Help Evaluate
The Advanced OAT Test provides metabolic insight clinically relevant across a broad spectrum of chronic and complex conditions — particularly those that conventional investigation has failed to explain:
Autism Spectrum Disorder
ADHD
Chronic Fatigue Syndrome / ME
Fibromyalgia
Depression
Anxiety Disorders
OCD
Parkinson’s Disease
Dementia / Alzheimer’s
Seizure Disorders
IBS & Gut Dysbiosis
SIBO
Recurrent Candida
Autoimmune Disorders
Diabetes / Insulin Resistance
Cardiovascular Disease
Obesity & Metabolic Syndrome
Hormonal Imbalances
Thyroid Dysfunction
Nutritional Deficiency Syndromes
BPA / Xylene / Chemical Exposure
Mycotoxin & Mould Illness
Heavy Metal Toxicity
Lyme & Tick-Borne Diseases
Post-COVID Fatigue
Poor Athletic Recovery
Unexplained Chronic Symptoms
Frequently Asked Questions — Advanced OAT Test
Is the Advanced OAT Test a blood test or a urine test?
The Advanced OAT Test is a urine-based test. You collect a first morning urine sample at home using the kit we dispatch to your address. No blood draw, no venepuncture, no laboratory visit, and no needle of any kind is required. This makes it particularly suitable for children and individuals with needle anxiety.
What is the Advanced OAT Test price at Altus Diagnostic?
The Advanced OAT Test is priced at ₹18,000 at Altus Diagnostic. This includes the home collection kit, prepaid courier return, LC-MS/MS laboratory analysis of all 140+ biomarkers, calculation of 21 functional ratio indices, and the full NABL accredited report delivered digitally. To book, call or WhatsApp +91 89680 10467.
How long does the Advanced OAT Test report take?
The report is delivered within 7 working days of the laboratory receiving your sample — not from the date of collection. The report is sent digitally via email and WhatsApp as a detailed PDF, immediately shareable with your specialist or functional medicine practitioner.
Why does fasting matter for the Advanced OAT Test?
Fasting is essential for an accurate result. An overnight fast of 10 to 12 hours ensures that the organic acid profile reflects your underlying metabolic baseline — not the immediate effects of recent food consumption. Water is permitted throughout the fast. Collecting first morning urine after the overnight fast provides the most concentrated and clinically meaningful specimen.
Can children take the Advanced OAT Test?
Yes. The Advanced OAT Test is suitable for children of all ages and is particularly valuable for paediatric neurodevelopmental investigations — including autism, ADHD, speech delay, and developmental regression. Urine collection for children is straightforward with the kit materials provided. For infants, our team guides parents through the appropriate collection technique. Call +91 89680 10467 for paediatric collection guidance.
Should I stop supplements before the Advanced OAT Test?
It depends on the supplement. High-dose B vitamins, probiotics, antifungal agents, and antibiotics can all influence specific OAT results. As a general principle, stopping non-essential supplements 5 to 7 days before sample collection provides the most accurate baseline metabolic picture. Contact our team for specific guidance before your collection.
What technology does Altus Diagnostic use for the Advanced OAT Test?
Altus Diagnostic uses Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS) — the gold standard in clinical metabolomics. LC-MS/MS provides simultaneous quantification of 140+ metabolites with femtomolar sensitivity and exceptional specificity, endorsed by international clinical metabolomics bodies and providing the analytical precision required to measure low-concentration urinary organic acids reliably.
How is the Advanced OAT Test different from a standard urine or kidney test?
A standard urine analysis tests for protein, glucose, creatinine, and a handful of electrolytes — specifically to assess kidney health. The Advanced OAT Test measures 140+ metabolic byproducts related to how your mitochondria, gut microbiome, liver detoxification, neurotransmitters, and vitamin metabolism are functioning. These are entirely different investigations with entirely different clinical purposes.
Can the Advanced OAT Test be done alongside the FRAT Test?
Yes — and for children with autism or suspected Cerebral Folate Deficiency, doing both is clinically complementary. The FRAT Test determines whether folate transport to the brain is blocked by autoantibodies. The Advanced OAT Test reveals what is happening downstream as a consequence — the gut dysbiosis, mitochondrial impairment, oxidative stress, and neurotransmitter imbalances that result from or accompany CFD. Together they provide the complete picture needed for a comprehensive intervention protocol. Learn more about the FRAT Test at Altus Diagnostic.
Is the Advanced OAT Test NABL accredited?
Yes. The Advanced OAT Test at Altus Diagnostic is processed under NABL accreditation — India’s National Accreditation Board for Testing and Calibration Laboratories. NABL accreditation certifies that the analytical processes, instrument calibration, quality controls, and reporting standards meet national and international quality specifications. Reports are accepted by functional medicine practitioners, integrative specialists, and hospitals across India.
Book Your Advanced OAT Test Today
Kit delivered to your home anywhere in India · NABL accredited report in 7 working days · LC-MS/MS technology · 140+ biomarkers · 21 functional indices
₹18,000
140+ Biomarkers · 21 Indices
NABL Accredited · 7-Day Report
Kit-Based · Home Collection
NABL Accredited · 7-Day Report
Kit-Based · Home Collection
Clinical Note: The Advanced OAT Test is intended to support functional and integrative medical assessment. Results should be interpreted by a qualified functional medicine practitioner or integrative physician in the context of the patient’s full clinical history, examination findings, and other investigations. This page is for educational and informational purposes and does not constitute medical advice or a clinical diagnosis.