AUTOIMMUNE ENCEPHALITIS (NMDA+VGKC)

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AUTOIMMUNE ENCEPHALITIS (NMDA+VGKC)

  • AUTOIMMUNE ENCEPHALITIS(N-METHYL-D-ASPARTATE + VOLTAGE-GATED
    POTASSIUM CHANNEL)

    PNEUMONIC’S =Autoimmune Encephalitis Panel
    NMDA (anti-glutamate receptor against NR1 subunit)
    AMPA (anti-glutamate receptor) – GluR1
    AMPA (anti-glutamate receptor) – GluR2
    GABA-B receptor antibody
    LGi-1 antibody (VGKC type)
    CASPR2 antibody (VGKC type)
    *PERFORMING LAB = ALTUS LAB (IN HOUSE)
    *REPORTING TIME = 4 to 5 DAYS
    *CLINICAL SIGNIFICANCE
    = Autoimmune encephalitis is a collection of related
    conditions in which the body’s immune system attacks the brain, causing
    inflammation. The immune system produces substances called antibodies that
    mistakenly attack brain cells.